CONTENTS
PHARMACOEPIDEMIOLOGIC ANALYSIS OF TREATMENT OF IRON-DEFICIENT ANAEMIA IN CHILDREN OF EARLY AGE GROUP AND THEIR MOTHERS IN OUTPATIENT SETTINGSThe current practice of prescription of drugs to children of early age with iron deficient anaemia and their mothers during pregnancy in outpatient conditions is studied. 562 ambulatory charts of children of early age and charts of their mothers during pregnancy are analyzed. ADAPTIVE RESOURCES OF TEENAGERS WITH FREQUENT EPISODES OF ACUTE RESPIRATORY DISEASESPsychovegetative status and colonized resistance indices of oral cavity in teenagers with frequent respiratory diseases are studied. The correlation between repeated episodes of acute respiratory diseases and state of adaptive resourses of organism is revealed. Obviously, the changes of psychologic status and vegetative dysfunction result in destabilization of protection mechanisms promoting invasion of pathogenic microorganisms. DEPENDANCE OF THE FORM OF INFANTILE CEREBRAL PALSY ON GESTATION AGE AT BIRTHThe combined examination of 266 patients aged one year to 18 years with infantile cerebral palsy is carried out to study the effect of gestation age at birth on the formation of various forms of infantile cerebral palsy. It is revealed that prematurity is a high risk factor of the development of the most frequent clinical form of infantile cerebral palsy - spastic diplegia determining the necessity of promotion of treatment and rehabilitative measures in premature children. Right-sided hemiparesis resulting from a lesion of functionally dominant left cerebral hemisphere is more often in mature children. CLINICAL IMPORTANCE OF ZINC IN ACUTE PNEUMONIAS AND BRONCHITIS IN CHILDRENIn studies of the content of serous zinc its significant deficiency is revealed in patients with the focal form of acute pneumonia and relapsing bronchitis. The clinical course of these diseases was characterized by long-term persistance of physical changes along with practically unchanged indices of hemogram. In cases of additional prescription of zinc sulphate to the basic treatment of patients with acute pneumonia and potassium fumarate to patients with relapsing bronchitis the terms of improvement of clinical symptoms of inflammation have been accelerated and zinc level in serum has been increased. DRUG RESISTANCE OF ESHERICHIA COLI IN ASYMPTOMATIC BACTERIURIA AND BACTERIOLACTIAResults of the study of sensitivity to antibiotics of E. coli strains isolated from urine and feces of children with asymptomatic bacteriuria and intestin dysbacteriosis as well as from milk of mothers with bacteriolactia are given. E. coli isolated from breast milk was the most resistant to the studied antibacterial drugs. PREVENTION OF PERINATAL HIV-INFECTIONThe experience of perinatal prevention of HIV-infection is discussed. 155 children delivered by HIV-infected women were observed. The presence of basic risk factor of infection - the acute stage of HIV-infection in mothers during pregnancy, delievery and lactation is established in most cases of perinatal infection. All three stages of perinatal chemoprophylaxis are carried out only in 60% of women giving birth. Timely onset of prevention took place in 38% of women. Incomplete inclusion of HIV-infected pregnants into perinatal prevention was more often determined by late diagnosis of HIV-infection and lack of complience of patients due to using drugs. DIAGNOSIS OF POSTOPERATIVE DYSPHAGIAS IN ESOPHAGEAL ATRESIASBased on experience of treatment of 68 patients with atresias of esophagus new examination methods are described. Roentgenoesophagoscopy performed on the angiographic apparatus and fibroesophagoscopy proved to be the most informative for differential diagnosis of postoperative dysphagias in children with atresia of esophagus. It is reasonable to begin examination of patients with fibroesophagoscopy. It does not require expensive equipment and is not accompanied by irradiation. Roentgenoesophagoscopy on the angiographic apparatus should be performed only in cases when fibroesophagoscopy does not provide answers to all questions or when risk during its performance is very high. CHOICE OF MÀNAGEMENT IN PATIENTS WITH VARICOCELE93 adolescents with varicocele are examined. Different variants of pathology of testicular basin veins like compression of renal vein in aortomesenteric segment with high gradient of pressure between left renal and inferior cava veins like; compression of left common iliac vein; stenosis of left renal and inferior cava veins; compression of left common iliac vein; stenosis of left renal vein and sinistroposition of the abdominal part of inferior cava vein with compression in aortomesenteric segment are revealed in 31 of adolescents during phleborenography with tensiometry. Combined pathology is revealed in 4 adolescents. Classification of phleborenohypertension is suggested. Depending on its manifestation the indications for operative interventions are defined. Operations included different options starting from classical operation by Ivanissevich to extravasal correction of left renal vein. PROLONGED MICRODRAINAGE IN PREVENTION OF MEDIASTINITIS AFTER MEDIAN STERNOTOMY IN CARDIOSURGICAL PATIENTSSignificance of prolonged microdrainage in prevention of anterior mediastinitis after operations on open heart is studied. It is established that this method of drainage of wound canal makes it possible to control the course of wound process, to ajust the treatment, to prevent pyo-septic complications in patients operated by sternotomy without opening the pleural cavities. XIMEDONE IN COMBINED TREATMENT OF PATIENTS WITH ULCERATIVE GASTRODUODENAL BLEEDINGResults of the treatment of 223 patients with ulcerative gastroduodenal bleeding are analyzed. After hemostasis with medications the relapse of acute gastroduodenal bleeding is noted in 28 (12,6%) patients, 16 (11%) of whom had duodenal ulcer and 12 (19,8%) patients - gastric ulcer. Antibacterial effect of ximedone towards H. pylori is established by microbiologic studies. Possibilities of including this drug in combined treatment of patients with ulcerative gastroduodenal bleeding in order to decrease the number of relapses are considered. INTRAOPERATIVE HYPOTHERMAL SANATION OF PERITONEUM IN THE ÒREATMENT OF PATIENTS WITH DIFFUSED PURULENT PERITONITISThe use of intraoperative hypothermal sanation of peritoneum in combined treatment of 74 patients with diffused purulent peritonitis of various genesis made it possible to reduce the incidence of postoperative complications from 68,2 to 29,7% and lethality - from 22,7 to 16,2%. ULTRASOUND MORPHOLOGY OF KNEE JOINT MENISCUS240 knee joints in males and females aged 6 to 76 years with suspicion on injury of meniscus are examined. The complex of signs characterizing normal structure and functioning of meniscus tissue is developed. Ultrasound equivalents of destruction of basic and fibrous components of matrix starting from preclinical stage of development are revealed. Ultrasound criteria of injury of meniscus and peculiarities of the reparation course are determined. HEREDITARY FACTORS OF THE DEVELOPMENT OF ESSENTIAL ARTERIAL HYPERTENSION, PECULIARITIES OF ITS COURSE AND CHOICE OF HYPOTENSIVE THERAPYPolymorphism of the T174M gene of angiotensinogen in patients with essential arterial hypertension of Kazan population is studied. It is established that studies of hereditary factors of the development of essential arterial hypertension make it possible to distinguish persons requiring primary prevention with regard to their genotype. Selective prescription of b-adrenoblockers in the TT genotype and ACE inhibitors in the TM gene of angiotensinogen will make it possible to control timely and efficiently the level of arterial pressure and to decrease expenses of patients. PECULIARITIES OF PORTAL BLOOD CIRCULATION AND ECHOGRAPHIC STRUCTURE OF LIVER IN PATIENTS WITH CHRONIC HEART FAILUREGeneral clinical and laboratory examination, electrocardiography, echocardiography, ultrasound and doppler examination of liver were carried out in 109 patients with chronic heart failure and 31 patients of the control group. Portal hemodynamics parameters in chronic heart failure of the I-II functional class did not differ from those in the control group and three types of portal system reactivity are revealed in the III-IV functional classes. The most unfavourable type of portal system reaction, accompanied by progressive aggravation of state of patients by echocardiography and boderline videodensitometry is the third type of reaction. |