CONTENTS
PERIARTICULAR TISSUE IN PATIENTS WITH RHEUMATOID ARTHRITIS AND OSTEOARTHRITISThe extent of inflammation and degeneration in osteoarthritis and rheumatoid patients with periarticular tissue lesions was estimated in 88 patients with painful knee. It was found that periarticular tissue lesions were associated with signs of degentration (joint space narrowing, osteophytes). Disease activity and synovitis in rheumatoid patients significantly increased the involvement of soft tissues. MULTIFOCAL ASEPTIC BONE NECROSISEndoprostetic hip replacement operation was made to three patients with aseptic hip necrosis. Roentgenography of arms due to local pain showed pathological changes in the caput of arm bone. The possible reasons for multifocal aseptic bone necrosis are discussed. THE ROLE OF HYPOXIA IN THE PATHOGENESIS OF COMBINED CARDIO-RESPIRATORY PATHOLOGY366 patients with isolated and combined cardio-respiratory disorders were involved in the study. It was found that chronic hypoxia played important role in the pathogenesis of the severity syndrome in patients with coronary disease combined with chronic obstructive pulmonary disease. DIASTOLIC CARDIAC FUNCTION IN PATIENTS WITH TYPE 1 DIABETES MELLITUSIntracardiac circulation disturbances were studied in patients with type 1 diabetes mellitus. It was found that in these patients the most sensitive indicators of intracardiac circulation disturbances were the maximal rates of early and late peak of diastolic trans-mitral blood flow, the ratio of the maximal rate of early peak to the maximal rate of late peak of diastolic trans-mitral blood flow, and the time of isovolumetric relaxation of the myocardium. ENDOTHELIAL AND CELL-MEMBRANE EFFECTS OF NEBIVOLOL AND TRIMETAZIDINEThe effectiveness of nebivolol in combination with trimethazidine was studied in patients with acute coronary syndrome without ST elevation. It was found that nebivolol normalized the endothelium-dependent vasodilatation, while trimethazidine stabilized cell membranes in these patients. THE EFFECTIVENESS AND SAFETY OF "FOZIDE" IN PATIENTS WITH ARTERIAL HYPERTENSIONThe effectiveness of "Fozide" was studied in patients with mild and moderate arterial hypertension. It was found that treatment with "Fozide" caused prolonged antihypertensive and nephroprotective effects without adverse reactions. LASER THERAPY OF PATIENTS WITH STABLE ANGINAThe efficacy of laser therapy was estimated on 160 patients with stable angina; 56 patients received only specific medication care, while 104 patients were treated also by laser therapy. It was found that the laser therapy on acupuncture dotes of heart and pericardium meridians improved patients' condition, increased elasticity of the muscle-type vessels, and enhanced tolerance to physical exercises. In patients with functional class I-II the achieved effect was sustainable for 6 months and in patients with functional class III-IV - for 3 months. THE ROLE OF COMBINED STRESS-ECHOCARDIOGRAPHY METHODS IN NON-INVASIVE EVALUATION OF THE RESULTS OF SURGICAL TREATMENT OF ISCHEMIC HEART DISEASEThe effectiveness of combined stress-echocardio-graphy methods was evaluated in 69 male patients (of 37-58 years of age) with angina after balloon angioplasty and stentation operations. Stenosis of more than 75% of arterial diameter was revealed in 38 patients with preoperative stress-echocardiography, stenosis of 50-75% was revealed in 30 patients, and only one patient had 40% of coronary stenosis. Postoperative stress-echocardio-graphy showed that there were no hypokinetic zones in 67 patients and the number of hypokinetic zones decreased in two other patients. IS THERE ANY CORRELATION BETWEEN NEUROLOGICAL AND PSYCOLOGICAL SEQUELAE OF TRAUMATIC BRAIN INJURY?The aim of the study was to investigate neurological versus psychological changes in early and late periods of traumatic brain injury (TBI). 89 patients with mild and moderate TBI were examined, including 40 from 4 to 15 days and 49 from 6 months to 5 years after the injury. In addition to neurological examination and CT scan, the psychological status was assessed using the Leonhard's questionnaire, a test for neurosis, and the abridged MMPI test. The neurological and psychological disorders displayed some correlations in the late period regarding severity and incidence of neurotic and vegetative symptoms. At the same time, the manifestations of psychological disorders neither depended on early and late focal neurological deficit, nor were they associated with CT-positive focal damage of brain matter. The data are consistent with the hypothesis that the deferred psychological disorders have psychogenic nature, rather than are due to organic brain damage. In addition, the early course of mild and moderate TBI seems to have a limited impact on the late neurological and psychological sequelae of TBI. THE CURRENT SITUATION AND PERSPECTIVES OF SURGICAL TREATMENT OF PATIENTS WITH PULMONARY TUBERCULOSIS IN THE REPUBLIC OF BASHKORTOSTANThe statistical analysis of the results of the surgical treatment of 11918 patients with pulmonary tuberculosis treated in Ufa pulmonary-surgical center in 1966-2004 was carried out. The majority of patients (94,1%) had clinical forms of secondary tuberculosis. The surgical procedures included all types of pulmonary resection: the economy ones, pneumoectomia, toracoplastic operations and extraction of lymphatic nodes. Postoperative complications were registered in 13,9% patients, postoperative mortality was 0,1-1,2%. Effectiveness of surgical treatment was achieved in 96,1% patients, professional rehabilitation was achieved in 90,5% patients. . MICROVESICULATION IN PHYSIOLOGICAL DELIVERY AND CESAREAN SECTIONThe total number of microvesicles and expression of procoagulant phosphatidylserine were evaluated in circulation and retroplacental blood of women during physiological delivery and cesarean section. The principal differences in women after cesareans were characterized by high expression of phosphatidylserine in microvesicles in peripheral blood and microvesiculation out of placental place. THE EFFECTS OF OZONO-TREATED CRISTALLOIDS ON LIPID PEROXIDATION PROCESSES AT EARLY POSTOPERATIVE PERIODS OF ONCOLOGICAL PATIENTS170 patients (40-79 y.o.) were under postoperative observation due to operation on gastrointestinal tract. Traditional postoperative medications were given to all patients, while patients of the study group on top of that have received the ozonotherapy. Lipid peroxidation products' levels were measured before and after treatment. It was found that the lipid hydroperoxides' and molonic dialdehide plasma levels were significantly decreased in ozon-treated patients, while no changes were detected in other patients. Ozonotherapy reduced the activity of lipid peroxidation, which was documented by the decrease of intermediate and final concentrations of its products. LIPID PEROXIDATION AND ENZYMATIC CHAIN OF BLOOD ANTIOXIDANT SYSTEM IN OVARIAN CARCINOMAThe correlation between lipid peroxidation products and antioxidants plasma levels has been evaluated in 52 women with ovarian carcinoma and 30 postmenopausal healthy donors. It was found that plasma level of peroxidation-antioxidant system components was markedly increased in patients at the II-III clinical stages of the disease and was decreased - in the terminal period. TRAUMATIC BRAIN INJURY IN KAZANStatistical analysis of incidence, principal causes, death rate and distribution of traumatic brain injury in Kazan in 2002 was given. Although overall lethality of traumatic brain injury is 10.6%, the greatest danger for life was found to be road accidents where death rate was 26,4%. © 1995-2008 Kazan State University |