CONTENTS
CLASSIFICATION OF VARICOCELE SYNDROME IN TEENAGERSDue to problems of diagnosis and treatment of varicocelle syndrome in teenagers and absence of universal clinical, ethyological and pathogenetical classification of varicocelle, the evolution of views to build such classification as well as a working variant of it is presented. RELATIONSHIP BETWEEN LEVELS OF EXTRACELLULAR DNA AND ANTIBODIES AGAINST DOUBLE STRANGE DNA IN NEW BORNS WITH PNEUMOPATHYRelationship between extracellular DNA amount and the level of antibodies against double strange DNA (dsDNA) was studied in newborns with pneumopathy. The concentration of extracellular DNA was measured by fluorescent spectrophotometry, the level of nuclear DNA by scanning light microscopy, the level of antibodies by ELISA. It was found that in newborns with pneumopathy the level of nuclear DNA is significantly decreased while the concentration of extracellular DNA is increased. A correlation between concentration of extracellular DNA and level of antibodies against dsDNA was established and that has an exponential manner. GENOM INSTABILITY IN PATIENTS WITH QUINSY AND ITS CORRECTION BY XYMEDONUMThe genom condition and the level of micronuclei in erythrocytes and number of aberrations in lymphocytes were studied in 179 patients with quinsy. It was found that during the acute period of disease and during the periods of recovery most of the patients displayed higher level of micronuclei and reconstruction of chromosomes in blood cells comparing with that of healthy people. Addition of an immunomodulator xymedonum to the complex therapy leads to the decrease of number of erythrocytes with micronuclei and lymphocytes with chromosomes aberrations to the level of healthy people and accompanies by the reduction of main symptoms of the disease. POSTRADIATION INJURIES OF LUNG TISSUE AFTER COMBINE TREATMENT OF HODGKIN LYMPHOMAThe results of combine chemo and radiation therapy of 100 patients with Hodgkin lymphoma is reported. The discrepancies between clinical status of the patients and roentgenological changes in the lung were found. It is suggested that all patients after radiation therapy have to pass roentgenological chest examination to check any small changes in the lung even without clinical manifistation. GENETIC POLYMORPHISM OF N-ACETYL-TRANSFERASE IN PATIENTS WITH CHILD CEREBRAL PALSYActivity of N-acetyltransferase was studied in 89 children with child cerebral palsy (CCP). Patients with CCP were predominantly low acetylisers. Children with a fast acetylisation process had relatively low incidence and milder type of CCP. A risky group for CCP includes those children who have the activity of N-acetyl-transferase of 7.1% and higher and with unfavourable time course during intra-uterine and perinatal periods. An index to calculate the relative risk to have CCP for patients with low type of acetylation was introduced. METABOLIC ASPECTS OF TREATMENT OF BRONCHOPULMONARY DISEASES IN CHILDREN BY SUCCINAT AND FUMARAT SALTSTherapeutic usage of succinat and fumarat salts in treatment of children with bronchopulmonary diseases is reported. New regimens with relation to age dosages are introduced. It was found that the usage of these salts in treatment of children with high incidents of respiratory diseases lead to quick normalization of clinical and laboratory signs of diseases. ACUTE INTESTINAL INFECTIONS IN CHILDREN TAKING BREAST MILK CONTAMINATED BY GRAM-NEGATIVE FLORAA clinico-bacteriological analysis of incidents of acute intestinal infections (AII) in children taking breast milk contaminated by gram-negative rods was performed. The peculiarities of AII due to Klebsiella was shown in relation to age, premorbid status, intensity of milk contamination. DIET-DEPENDENT CONDITIONS OF MINERAL STATUS AND ACTIVITY OF ENZYMES OF THE ANTIOXIDATIVE SYSTEM IN CHILDRENHealth condition of children living in two districts of Kazan supplied with the drinking water of contrast mineral composition was studied. The higher level of gastroduadenal pathology was found in a group of ecological risk. ANTIHELICOBACTER THERAPY IN THE TREATMENT OF ULCERATIVE GASTRODUODENAL HEMORRHAGESThe comparative study of several regimens of eradication therapy was performed on 106 patients with ulcerative gastro-duodenal hemorrhages associated with Helicobacter pylori. A new eradication regimen was introduced which includes omeprasol together with ximedon. The eradication efficacy of such bi-component therapy was 95.2% and that associated with positive endoscopic and morphological signs of the recovery of ulcer. THE USAGE OF OZONATED ERYTHROCYTE MASS IN THE TREATMENT OF ULCERATIVE GASTRODUODENAL HEMORRHAGESThe analysis of the treatment results of 328 patients with ulcerative gastro-duodenal haemorrhages showed that main reasons for postoperative mortality were acute myocardial infarct, acute cerebrovascular insufficiency, and pulmonary artery thromboembolia. The same reasons caused the high mortality of non-operated patients. The authors introduce a new method of ozonotherapy, which does not reduce the blood coagulation but in contrast normalizes heamocoagulation factors. After using ozone according to the author's method postoperative mortality reduced from 24.7% to 16.7%. NUTRITION SUPPORT IN PURULENT SEPTIC SURGERYIt was found, that early adequate nutrition support of a patient by combined methods of parenteral and enteral nutrition is the most effective way of correction of protein and energy metabolism in critical conditions. Usage of Nutricomp Fiber mixture by patients at postoperative stage optimized the management of inflammatory processes. PECULIARITIES OF DIAGNOSIS AND TREATMENT OF CHRONIC CONSTIPATION IN CHILDRENComplex observation of 120 children with chronic constipation (age from 8 months to 14 years) revealed organic (Hirshprung disease - 20%) and functional (megarectum - 45.83%; megarectum with megacolon - 21.67%, dolichisigma - 12.5%) ethyology of the disease. Surgical methods of treatment were used in organic ethyology, while different methods of conservative treatment were used in functional diseases. THE ROLE OF EXAMINATION OF MATERNAL HAEMODYNAMICS IN THE VALUATION OF TREATMENT OF LATE GESTOSISThe parameters of maternal haemodynamics were studied by volumetric compressive oscillometry method in 75 patients with uncomplicated pregnancy as well as in women with pregnancy complicated by light (32 patients), mild (18 patients) and severe (6 patients) gestosis. Hypotensive therapy was based on the type of haemodynamics. Assessment of gestosis with individually oriented complex therapy had positive influence on outcome of pregnancy. EVALUATION OF DUCTOGRAPHY IMPORTANCE IN PATHOLOGICAL SECRETION FROM THE NIPPLESDuctography was performed for the period of 2002-2005 in 108 women with spontaneous secretion from nipples. Ductography is a method of choice in women with pathological secretion from nipples. However negative or doubtful results are indications for MR-ductography, which is a highly specific method to eliminate malignant disorders and therefore to reduce a number of unnecessary surgical treatment. EFFECT OF ENDOTOXINEMIA ON GESTATION AND OUTCOMES OF DELIVERIES IN PREGNANT WOMEN WITH CONSTIPATIONIntestinal microflora and endotoxemia were studied in 25 pregnant with constipation. In particular, chophytol, the choleretic agent, was found to optimise activity of intestinal microflora, relieve endotoxemia and improve constipation in the majority of the patients, which is expected to reduce risk of the development of gestational and parturient complications. THE USAGE OF ENDOCERVICAL GEL WITH PROSTAGLANDIN E2 IN PREGNANT WOMEN WITH SCAR AFTER CESAREAN SECTION FOR PREPARATION OF CERVIX TO DELIVERYThe efficacy of endocervical gel with prostaglandin E2 was tested on 27 pregnant women with scar on the uterus due to earlier cesarean section. It was found that when the scar is efficient and a woman is willing to deliver physiological way, gel with prostaglandin E2 is very effective for preparation of cervix to parturition. © 1995-2008 Kazan State University |